Real Time PCR Detection Kit Vancomicin resistance vanB

The Real Time PCR detection Kit Vancomicin resistance vanB comprises a series of specific targeted reagents designed for Vancomicin resistance vanB detection by using qPCR.

GENERAL INFORMATION:Vancomycin is a glycopeptide used for its bactericidal effect to treat infections caused by Gram-positive bacteria. It binds to the bacterial cell envelope rather than to a protein target, as is the case for other antibiotics. Vancomycin’s therapeutic efficacy is threatened by two types of complex resistance mechanisms, each involving a multi-enzyme route, that are becoming extensively more common in pathogenic species. The vanB resistance gene cluster resides on the transposon Tn1547, more commonly found in bacterial chromosomes, but it can also be found on plasmids. Only vancomycin, but not teicoplanin, induces vanB resistance.

KIT CHARACTERISTICS:
- Assay Mix Target composed by singleplex mixtures of specific forward/reverse primers and probe.
- Resuspension buffer
- DNase/RNase free water
- (OPTIONAL) Internal Control Assay Mix
- Mastermix solution
- Positive control