Kit de deteção de PCR em tempo real Leishmania infantum (complexo Leishmania donovani)

O kit de deteção de PCR em tempo real Leishmania infantum (complexo Leishmania donovani) compreende uma série de reagentes específicos concebidos para a deteção de Leishmania infantum (complexo Leishmania donovani) utilizando qPCR.

GENERAL INFORMATION:Leishmania infantum (syn. L. chagasi) is a flagellated protist and one of the causative agents of the visceral leishmaniasis in the Mediterranean region and in Latin America. Leishmaniasis is a zoonotic disease, being wild canids and domestic dogs are the natural reservoir of this organism. Transmission is predominantly vector-borne, but vertical transmission between hounds has been confirmed. Visceral leishmaniasis, caused by L. infantum and L. donovani, is the most severe form of human leishmaniasis and it is often lethal if left untreated. Visceral leishmaniasis infections are often recognized by fever, swelling of the liver and spleen, and anemia. In dogs, L. infantum, is the most common and important cause of canine leishmaniasis worldwide. Treatment of canine leishmaniasis is less effective than the treatment developed for human use, since no drug has proven to be consistently curative for visceral leishmaniasis in dogs.

KIT CHARACTERISTICS:
- Mistura do ensaio composta por misturas singleplex de primers específicos de sentido direto/indireto e sondas.
- Tampão de ressuspensão
- Água livre de DNase/RNase
- (OPCIONAL) Mistura de controlo interno do ensaio
- Solução de mastermix
- Controlo positivo